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Mosquito known to transmit malaria has been detected

Mosquito known to transmit malaria has been detected

A type of mosquito that transmits malaria has been detected in Ethiopia for the first time, and the discovery has implications for putting more people at risk for malaria in new regions, according to a study led by a Baylor University researcher. The mosquito, Anopheles stephensi, normally is found in the Middle East, Indian Subcontinent and ...

Parasites from patients with cerebral malaria stick

Parasites from patients with cerebral malaria stick

A team at LSTM with their collaborators in Malawi and Denmark have provided, for the first time, evidence which links the ability of red blood cells infected with the malaria parasite to bind to the cells lining the blood vessels of the brain, with the clinical syndrome cerebral malaria. Cerebral malaria is a life-threatening complication ...

Malaria vaccine passes test in humans

Malaria vaccine passes test in humans

For many years, a team of researchers at the University of Copenhagen have been focussing on developing a vaccine that can protect against the disease pregnancy malaria from which 220,000 people die every year. Now they have come a significant step closer to being able to introduce such a vaccine in the market. In a ...

Fighting human disease with birth control … for mosquitoes

Fighting human disease with birth control … for mosquitoes

Depending on where you live, the buzz of a nearby mosquito can be a nuisance, or it can be deadly. Worldwide, more than 500 million people suffer from diseases transmitted by the blood-feeding insects, including malaria, Dengue Fever, Zika, and West Nile, and nearly a million deaths are attributed to mosquito-borne illnesses each year. Researchers ...

Pyronaridine-artesunate for treating uncomplicated Plasmodium

Pyronaridine-artesunate for treating uncomplicated Plasmodium

Researchers from LSTM have looked at the efficacy of using a novel artemisinin-based combination therapy (ACT), pyronaridine-artesunate, to treat malaria in areas where resistance to other ACTs is becoming a problem. The analysis finds it at least as effective as the currently used ACTs, if not better. The World Health Organization (WHO) recommends ACTs to ...

ERADA launches first diagnostic saliva test for malaria

ERADA launches first diagnostic saliva test for malaria

ERADA Technology Alliance Ltd (ERADA), pioneers of innovative, rapid diagnostic solutions for early detection of infectious diseases, have announced the imminent launch of a world first diagnostic saliva test for malaria. The saliva-based diagnostic tool, to be marketed by ERADA as a Saliva-based Malaria Asymptomatic and Asexual Rapid Test (SMAART) for subclinical infection, is set ...

For first time, researchers can measure insecticide

For first time, researchers can measure insecticide

Insecticide-infused mosquito netting is in widespread use around the world to limit the spread of mosquito-borne diseases, such as malaria. Researchers have now come up with a technique that measures how much insecticide is found on the surface of these nets -- paving the way for efforts to determine how long the nets are effective. ...

Gold-complexed ferrocenyl phosphines as potent antimalarials

Gold-complexed ferrocenyl phosphines as potent antimalarials

A team of researchers from the Singapore University of Technology and Design (SUTD) and Nanyang Technological University (NTU) have developed novel ferrocene-based molecules that impair the malaria parasite's metabolic function leading to parasite death. Despite concerted efforts for malaria elimination, this deadly disease remains a major health threat to the developing world. The causative agent ...

Baculovirus virion completely eliminates liver-stage parasites

Baculovirus virion completely eliminates liver-stage parasites

Currently, few antimalarial treatments exist that effectively kill liver-stage malaria parasites, which can lay dormant for months or years as in the case of <i>Plasmodium vivax</i>. Researchers from Kanazawa University have successfully demonstrated that administration of a baculovirus virion (BV) completely eliminates liver-stage parasites in a mouse model via BV-induced fast-acting innate immunity. Further development of ...

Researchers uncover a number of previously unknown

Researchers uncover a number of previously unknown

Researchers at LSTM have used a bioinformatics approach to integrate information from multiple studies on insecticide resistance in mosquitoes and uncovered a number of important resistance mechanisms that had not previously been recognized. In a study published in Nature Communications, Dr Victoria Ingham and colleagues have utilized specialist computer programming to better understand the mechanisms ...