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New insights into how the RTS,S malaria vaccine works

New insights into how the RTS,S malaria vaccine works

New Burnet Institute malaria research reveals: The RTS,S vaccine induces antibodies that recruit proteins in the blood to assist in blocking and killing malaria Prior exposure to malaria may have a bearing on the immune response The immune response declines rapidly within months of vaccination Burnet Institute scientists have made important discoveries about the workings …

Increase in cases of malaria

Increase in cases of malaria

Malaria is on the rise in South Africa because of the lack of urgency in dealing with the silent killer, experts warn. According to Goodbye Malaria, an NGO that aims to eliminate malaria in Africa, every minute or two a child under the age of five dies of the vector-borne disease. Pregnant women are also …

A retinal model of cerebral malaria

A retinal model of cerebral malaria

Malaria is a causative factor in about 500.000 deaths each year world-wide. Cerebral malaria is a particularly severe complication of this disease and thus associated with an exceedingly high mortality. Malaria retinopathy is an ocular manifestation often associated with cerebral malaria, and presumably shares a substantial part of its pathophysiology. Here, we describe that indeed …

New vaccine offers fresh take on malaria fight

New vaccine offers fresh take on malaria fight

"The problem with most vaccines is that their effectiveness is often short-lived," said the study's lead author, Klaus Früh, Ph.D., of OHSU's Vaccine & Gene Therapy Institute and a professor of molecular and cellular biosciences at the OHSU School of Medicine. "Our cytomegalovirus-based vaccine platform can create and keep immunity for life. With further research ...

Israeli AI firm fights malaria with machine learning

Israeli AI firm fights malaria with machine learning

Dozens of teams are competing to apply machine learning and artificial intelligence to solving serious social problems in the IBM Watson AI XPRIZE. A relatively late entry is Zzapp Malaria, which is working to eradicate one of humanity’s most persistent diseases. The company was recently named as one of the current top 10 teams in ...

New study raises hopes of eradication of malaria

New study raises hopes of eradication of malaria

After major global successes in the battle against malaria, the positive trend stalled around 2015—apart from in Zanzibar in East Africa, where the disease is increasingly rare. In a new study published in <i>BMC Medicine</i>, researchers at Karolinska Institutet in Sweden explain why this was and show that new strategies are needed to eradicate the disease. ...

Is malaria research leaving out the human factor?

Is malaria research leaving out the human factor?

What people do at night, when the risk of infected mosquito bites is highest, is especially critical, the authors say. There is substantial research into when malaria mosquitoes bite, when they are most active, and which species are most likely to spread disease, says April Monroe, senior program officer at the Johns Hopkins University’s Center ...